Group association test using a hidden Markov model

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چکیده

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Group association test using a hidden Markov model.

In the genomic era, group association tests are of great interest. Due to the overwhelming number of individual genomic features, the power of testing for association of a single genomic feature at a time is often very small, as are the effect sizes for most features. Many methods have been proposed to test association of a trait with a group of features within a functional unit as a whole, e.g...

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Title: Group Association Test Using a Hidden Markov Model

In the genomic era, group association tests are of great interest. Due to the overwhelming number of individual genomic features, the power of testing for association of a single genomic feature at a time is often very small, as are the effect sizes for most features. Many methods have been proposed to test association of a trait with a group of features within a functional unit as a whole, e.g...

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ژورنال

عنوان ژورنال: Biostatistics

سال: 2016

ISSN: 1468-4357,1465-4644

DOI: 10.1093/biostatistics/kxv035